The tumor protein D52 (TPD52) family consists of three members, TPD52, TPD52L1 (D53), and TPD52L2 (D54).
These small coiled-coil motif bearing proteins interact in hetero- and homomeric fashion.
The TPD52 gene maps to chromosome 8q21, and due to amplification, shows frequent overexpression in prostate and breast carcinomas.
TPD52 bound to annexin VI in a Ca2+-dependent manner, suggesting that these molecules may act in concert to regulate secretory processes in plasma cells.
Applications:Suitable for use in Immunohistochemistry and ELISA.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 1:100-1:300ELISA: 1:40,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of human TPD52. Species Crossreactivity: mouse
Isotype:IgG
Calc Applications Abbrev:E IHC
Calc Crossreactivity:Hu Mo
Immunogen:Synthetic peptide corresponding to aa10-90 of human TPD52.