84-5599-86 [取扱停止]TNFAIP8L3 100ul 543208
特徴
- TNFAIP8L3 (TNF alpha induced protein 8 like 3) is a protein coding gene.
- Among its related pathways are metabolism and glycerophospholipid biosynthesis.
- An important paralog of this gene is TNFAIP8.
- Acts as a lipid transfer protein.
- Preferentially captures and shuttles two lipid second messengers, i.e.
- phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol 3,4,5-trisphosphate and increases their levels in the plasma membrane.
- Additionally, may also function as a lipid-presenting protein to enhance the activity of the PI3K-AKT and MEK-ERK pathways.
- May act as a regulator of tumorigenesis through its activation of phospholipid signaling.
- Applications:Suitable for use in Western Blot and ELISA.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:10,000-1:20,000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:100ul
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Specificity:Recognizes endogenous levels of human TNFAIP8L3. Species Crossreactivity: mouse and rat
- Isotype:IgG
- Calc Applications Abbrev:E WB
- Calc Crossreactivity:Hu Mo Rt
- Immunogen:Synthetic peptide corresponding to aa15-45 from human TNFAIP8L3.
- Swiss Prot Number:Q5GJ75
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