The protein encoded by HAVCR1 is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4.
The encoded protein may be involved in the moderation of asthma and allergic diseases.
The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals.
Alternative splicing of HAVCR1 results in multiple transcript variants.
Related pseudogenes have been identified on chromosomes 4, 12 and 19.
HAVCR1 (hepatitis A virus cellular receptor 1) is a protein coding gene.
Diseases associated with HAVCR1 include hepatitis and hepatitis A.
Among its related pathways are T cell co-signaling pathway: ligand-receptor interactions and NF-kappaB signaling.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:10,000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human TIM-1.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa40-100 from human TIM-1.
