GTF2I encodes a phosphoprotein containing six characteristic repeat motifs.
The general transcription factor IIi binds to the initiator element (Inr) and E-box element in promoters and functions as a regulator of transcription.
This locus, along with several other neighboring genes, is deleted in Williams-Beuren syndrome.
There are many closely related genes and pseudogenes for this gene on chromosome 7.
This gene also has pseudogenes on chromosomes 9, 13, and 21.
Alternatively spliced transcript variants encoding multiple isoforms have been observed.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human TFII-I (phospho Tyr248). Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human TFII-I around the phosphorylation site of Y248.
