The product of TAF5L belongs to the WD-repeat TAF5 family of proteins.
TAF5L encodes TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65kD subunit 5L that is a component of the PCAF histone acetylase complex.
The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation.
TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation.
The TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65kD subunit 5L is structurally similar to one of the histone-like TAFs, TAF5.
Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Applications:Suitable for use in Western Blot, Immunohistochemistry, and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry (paraffin): 1:100-1:300ELISA: 1:10,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:30ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of human TAF5L. Species Crossreactivity: monkey
Isotype:IgG
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Hu Mk
Immunogen:Synthetic peptide corresponding to aa260-340 of human TAF5L.