TAF12 (TATA-box binding protein associated factor 12) is a protein coding gene.
Among its related pathways are formation of HIV elongation complex in the absence of HIV Tat and HIV life cycle.
Control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins.
These proteins with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site.
Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors.
Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex.
Among the latter are the TAF proteins.
Different TAFs are predicted to mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases.
TAF12 interacts directly with TBP as well as with TAF2I.
Two transcript variants encoding the same protein have been found for TAF12.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human TAF12. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to human TAF12 protein.
