The protein encoded by SRSF6 (serine and arginine rich splicing factor 6) is involved in mRNA splicing and may play a role in the determination of alternative splicing.
The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12.
Alternative splicing results in multiple transcript variants.
In addition, two pseudogenes, one on chromosome 17 and the other on the X chromosome, have been found for SRSF6.
Applications:Suitable for use in Immunohistochemistry, and ELISA.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 1:100-1:300ELISA: 1:20,000 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of human SRp55. Species Crossreactivity: mouse and rat
Isotype:IgG
Calc Applications Abbrev:E IHC
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to aa30-110 from human SRp55.