HTR1E (5-Hydroxytryptamine Receptor 1E) is a Protein Coding gene.
Diseases associated with HTR1E include attention deficit-hyperactivity disorder.
Among its related pathways are Signaling by GPCR and cAMP signaling pathway.
Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and serotonin binding.
An important paralog of this gene is HTR1F.
G-protein coupled receptor for 5-hydroxytryptamine (serotonin).
Also functions as a receptor for various alkaloids and psychoactive substances.
Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase.
Signaling inhibits adenylate cyclase activity.
Serotonin 5-ht1E receptors are primarily located in the frontal cortex, caudate putamen, claustrum, hippocampus, and amygdala.
The human 5-ht1E receptor gene has been localized to chromosome 6 (6q14-q15); the receptor is closely related to the serotonin 5-HT1F receptor.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human SR-1E.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa70-150 of human SR-1E.
