UBXN11 (UBX domain protein 11) encodes a protein with a divergent C-terminal UBX domain.
The homologous protein in the rat interacts with members of the rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region.
It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation.
It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways.
The 3' coding sequence of UBXN11 contains a polymoprhic region of 24 nt tandem repeats.
Several transcripts containing between 1.
and five repeat units have been reported.
Multiple transcript variants encoding different isoforms have been found for UBXN11.
Applications:Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry (paraffin): 1:100-1:300Immunofluorescence: 1:200-1:1000ELISA: 1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human Socius.
Isotype：IgG
Calc Applications Abbrev：E IF IHC WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa100-180 from the Internal region of human Socius.
