SMG9 (SMG9, nonsense mediated MRNA decay factor) is a protein coding gene.
Diseases associated with SMG9 include heart and brain malformation syndrome.
Among its related pathways are gene expression and viral mRNA translation.
SMG9 encodes a regulatory subunit of the SMG1 complex, which plays a critical role in nonsense-mediated mRNA decay (NMD).
Binding of the encoded protein to the SMG1 complex kinase scaffold protein results in the inhibition of its kinase activity.
Mutations in SMG9 cause a multiple congenital anomaly syndrome in human patients, characterized by brain malformation, congenital heart disease and other features.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human SMG9. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa70-150 from human SMG9.
