Diseases associated with SIX4 include holoprosencephaly 2.
Among its related pathways are mir-124 predicted interactions with cell cycle and differentiation and transcriptional misregulation in cancer.
SIX4 encodes a member of the homeobox family, subfamily SIX.
The drosophila homolog is a nuclear homeoprotein required for eye development.
Studies in mouse show that SIX4 product functions as a transcription factor, and may have a role in the differentiation or maturation of neuronal cells.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human SIX4. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to human SIX4 protein.
