SAP30 (Sin3A associated protein 30) is a protein coding gene.
Among its related pathways are chromatin organization and macrophage differentiation and growth inhibition by METS.
Histone acetylation plays a key role in the regulation of eukaryotic gene expression.
Histone acetylation and deacetylation are catalyzed by multisubunit complexes.
The protein encoded by SAP30 is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides.
This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones.
A pseudogene of SAP30 is located on chromosome 3.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human SAP30. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to aa140-220 from human SAP30.
