SAA1 gene encodes a member of the serum amyloid A family of apolipoproteins.
The encoded preproprotein is proteolytically processed to generate the mature protein.
This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury.
This protein also plays an important role in HDL metabolism and cholesterol homeostasis.
High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease.
This protein may also be a potential biomarker for certain tumors.
Alternate splicing results in multiple transcript variants that encode the same protein.
A pseudogene of this gene is found on chromosome 11.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human SAA1. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to human SAA1.
