RPS6KB1 (ribosomal protein S6 kinase B1) encodes a member of the ribosomal S6 kinase family of serine/threonine kinases.
The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation.
Activity of RPS6KB1 has been associated with human cancer.
Alternatively spliced transcript variants have been observed.
The use of alternative translation start sites results in isoforms with longer or shorter N-terminal which may differ in their subcellular localizations.
There are two pseudogenes for RPS6KB1 on chromosome 17.
Applications:Suitable for use in Western Blot, Immunofluorescence and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:1000-1:2000Immunohistochemistry: paraffinOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous p70 S6 kinase α. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：IF IHC WB
Calc Crossreactivity：Mo Rt
Immunogen：Recombinant protein corresponding to p70 S6 kinase α.
