POLR1D encoded by this gene is a component of the RNA polymerase I and RNA polymerase III complexes, which function in the synthesis of ribosomal RNA precursors and small RNAs, respectively.
Mutations in this gene are a cause of Treacher Collins syndrome (TCS), a craniofacial development disorder.
Alternative splicing results in multiple transcript variants.
POLR1D (RNA polymerase I subunit D) is a protein coding gene.
Diseases associated with POLR1D include Treacher Collins syndrome 2 and Polr1d-Related Treacher Collins syndrome.
Among its related pathways are pyrimidine metabolism (KEGG) and RNA polymerase III transcription initiation.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human RPAC2.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to human RPAC2 protein.
