The protein encoded by ROBO2 (roundabout guidance receptor 2) belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human.
The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration.
Mutations in ROBO2 are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney.
Alternative splicing results in multiple transcript variants.
Applications:Suitable for use in Immunohistochemistry, and ELISA.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 1:100-1:300ELISA: 1:40,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human Robo2. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa210-290 from the Internal region of human Robo2.
