84-5574-48　［取扱停止］RO52 100ul　541908

特徴

• TRIM21 encodes a member of the tripartite motif (TRIM) family.
• The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region.
• The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules.
• The RoSSA particle localizes to both the cytoplasm and the nucleus.
• RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus.
• Alternatively spliced transcript variants for TRIM21 have been described but the full-length nature of only one has been determined.
• Applications:Suitable for use in Western Blot and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.