RIPK1 encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases.
Receptor interacting serine/threonine kinase 1 plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation.
RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis.
Genetic disruption of this gene in mice results in death shortly after birth.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human RIPK1.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to human RIPK1 protein.
