84-5572-35　［取扱停止］Ribosomal Protein L22 30ul　541803

特徴

• Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
• Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins.
• RPL22 (ribosomal protein L22) encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit.
• The protein belongs to the L22E family of ribosomal proteins.
• Its initiating methionine residue is post-translationally removed.
• The protein can bind specifically to Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2.
• The mouse protein has been shown to be capable of binding to heparin.
• Transcript variants utilizing alternative polyA signals exist.
• As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
• It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1) gene located at 21q22 in some therapy-related myelodysplastic syndrome patients with 3; 21 translocations; however, these fusions actually involve a ribosomal protein L22 pseudogene located at 3q26.
• Applications:Suitable for use in Immunohistochemistry, and ELISA.
• Other applications not tested.
• Recommended Dilution:Immunohistochemistry (paraffin): 1:100-1:300ELISA: 1:10,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.