Members of the Ras superfamily of small GTP-binding proteins are critical mediators of diverse cell signaling pathways, including those leading to cell proliferation, cytoskeletal organization and secretion.
RERG (RAS-like, estrogen-regulated, growth inhibitor) is a 199aa protein that localizes to the cytoplasm and belongs to the Ras subfamily of small GTPases.
Expressed in pancreas, liver, skin, lung, brain, kidney and heart tissue, RERG possesses intrinsic GTPase activity and is able to bind both GDP and GTP and, when overexpressed, may reduce overall tumorigenic potential.
RERGL, also known as ras-related and estrogen-regulated growth inhibitor-like protein, is a 205aa protein that belongs to the small GTPase superfamily as well as the Ras family.
RERGL binds GDP/GTP and may possess intrinsic GTPase activity.
The RERGL gene is conserved in chimpanzee, dog, mouse, rat, chicken, zebrafish and mosquito, and maps to human chromosome 12p12.3.
Applications:Suitable for use in Immunohistochemistry, ELISA.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 1:100-1:300ELISA: 1:5000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human RERG. Species Crossreactivity: Mouse
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to aa70-150 from the Internal region of human RERG.
