MRAS encodes a member of the Ras family of small GTPases.
These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer.
The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways.
Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
MRAS (Muscle RAS Oncogene Homolog) is a Protein Coding gene.
Diseases associated with MRAS include Vertebral Artery Occlusion and Causalgia.
Among its related pathways are Arrhythmogenic right ventricular cardiomyopathy (ARVC) and p70S6K Signaling.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human RASM. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human RASM.
