RARA (retinoic acid receptor alpha)represents a nuclear retinoic acid receptor.
The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner.
RARA has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes.
Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia.
Alternatively spliced transcript variants have been found for this locus.
Applications:Suitable for use in Western Blot, Immunohistochemistry, and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry (paraffin): 1:100-1:300ELISA: 1:5000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human RAR alpha (phospho Ser77). Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human RAR alpha around the phosphorylation site of S77.
