PPP2R3C encodes a regulatory subunit of the serine/threonine phosphatase, protein phosphatase 2.
Potein phosphatase 2 regulatory subunit B''gamma is localized to both nuclear and cytoplasmic regions depending on cell cycle phase.
Homozygous conditional knockout mice for PPP2R3C exhibit reduced numbers and impaired proliferation of immune system B cells.
Potein phosphatase 2 regulatory subunit B''gamma may regulate the expression of the P-glycoprotein ATP-binding cassette transporter through its phosphatase activity.
Alternative splicing results in multiple transcript variants.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:30ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of human PPP2R3C. Species Crossreactivity: mouse and rat
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to aa140-220 of human PPP2R3C.