PPARG (peroxisome proliferator activated receptor gamma) encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors.
PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes.
Three subtypes of PPARs are known: pPAR-alpha, PPAR-delta, and PPAR-gamma.
The protein encoded by PPARG is PPAR-gamma and is a regulator of adipocyte differentiation.
Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer.
Alternatively spliced transcript variants that encode different isoforms have been described.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry (paraffin): 1:200-1:500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous PPAR-gamma protein. Species Crossreactivity: human, mouse and rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant protein corresponding to PPAR-gamma.
