Diseases associated with PLCB1 include Epile encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate.
This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals.
This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11.
Two transcript variants encoding different isoforms have been found for this gene.
PLCB1 (phospholipase C beta 1) is a protein coding gene.
Diseases associated with PLCB1 include epileptic encephalopathy, early infantile, 12 and malignant migrating partial seizuresoOf infancy.
Among its related pathways are calcium signaling pathway and long-term potentiation.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human PLCB1. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human PLCB1 protein
