PKD2 (polycystin 2, transient receptor potential cation channel) encodes a member of the polycystin protein family.
The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells.
This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis.
Mutations in PKD2 are associated with autosomal dominant polycystic kidney disease type 2.
Applications:Suitable for use in Immunofluorescence and ELISA.
Other applications not tested.
Recommended Dilution:Immunofluorescence: 1:200-1:1000ELISA: 1:10,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human PKD2. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E IF
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human PKD2 around the non-phosphorylation site of S812.
