Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways.
PI3K functions as a heterodimer of a regulatory and a catalytic subunit.
The protein encoded by PIK3R2 is a regulatory component of PI3K.
Two transcript variants, one protein coding and the other non-protein coding, have been found for PIK3R2.
PIK3R2 (Phosphoinositide-3-kinase regulatory subunit 2) is a protein coding gene.
Diseases associated with PIK3R2 include megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1 and mpph syndrome.
Among its related pathways are 4-1BB pathway and common cytokine receptor gamma-chain family signaling pathways.
Applications:Suitable for use in Immunohistochemistry, ELISA.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 1:50-1:200ELISA: 1:10,000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human PI 3-Kinase p85 Beta. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa1-60 from human PI 3-Kinase p85 Beta.
