BGN encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins.
The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues.
This protein may also regulate inflammation and innate immunity.
Additionally, the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients.
BGN and the related gene decorin are thought to be the result of a gene duplication.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of human PGS1. Species Crossreactivity: mouse and rat
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to aa110-190 from human PGS1.