PEX6 (peroxisomal biogenesis factor 6) is a protein coding gene.
Diseases associated with PEX6 include peroxisome biogenesis disorder 4A and Heimler syndrome 2.
Among its related pathways are peroxisome.
PEX6 encodes a member of the AAA (ATPases associated with diverse cellular activities) family of ATPases.
This member is a predominantly cytoplasmic protein, which plays a direct role in peroxisomal protein import and is required for PTS1 (peroxisomal targeting signal 1, a C-terminal tripeptide of the sequence ser-lys-leu) receptor activity.
Mutations in PEX6 cause peroxisome biogenesis disorders of complementation group 4 and complementation group 6.
Several transcript variants encoding different isoforms have been found for PEX6.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human PEX6. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa480-560 from human PEX6.
