PDCD1LG2 (programmed cell death 1 ligand 2) is a protein coding gene.
Diseases associated with PDCD1LG2 include cysticercosis and myasthenic syndrome, congenital, 14, with tubular aggregates.
Among its related pathways are T cell co-signaling pathway: ligand-receptor interactions and translocation of ZAP-70 to immunological synapse.
An important paralog of this gene is CD274.
Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner.
Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).
Applications:Suitable for use in Western Blot, Immunohistochemistry, ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry (paraffin): 1:500-1:200ELISA: 1:10,000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human PD-L2.
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa31-80 from human PD-L2.
