PARP9 (Poly(ADP-Ribose) Polymerase Family Member 9) is a Protein Coding gene.
Diseases associated with PARP9 include B-Cell Lymphomas and Lymphoma.
Among its related pathways are Metabolism and Metabolism of water-soluble vitamins and cofactors.
GO annotations related to this gene include NAD+ ADP-ribosyltransferase activity.
An important paralog of this gene is PARP14.
In concert with DTX3L plays a role in PARP1-dependent DNA damage repair.
PARP1-dependent PARP9/BAL1-DTX3L-mediated ubiquitination promotes the rapid and specific recruitment of 53BP1/TP53BP1, UIMC1/RAP80, and BRCA1 to DNA damage sites.
Involved in inducing the expression of IFN-gamma-responsive genes.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human PARP9. Species Crossreactivity: Mouse
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to aa450-530 from human PARP9.
