OPCML encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily of proteins.
Opioid binding protein/cell adhesion molecule like is proteolytically processed to generate the mature protein.
Opioid binding protein/cell adhesion molecule like is localized in the plasma membrane and may have an accessory role in opioid receptor function.
OPCML has an ortholog in rat and bovine.
The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein.
Since the opioid binding protein/cell adhesion molecule like is highly conserved in species during evolution, it may have a fundamental role in mammalian systems.
Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:10,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human OBCAM. Species Crossreactivity: mouse, rat, and monkey
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mk Mo Rt
Immunogen：Synthetic peptide corresponding to the Internal region of human OBCAM.
