84-5535-59 ［取扱停止］NUAK2 (NUAK Family Kinase 2) 100ul 539921
特徴
- NUAK2 (NUAK family kinase 2) is a protein coding gene.
- Among its related pathways are cytoskeletal signaling and glucose/energy metabolism.
- stress-activated kinase involved in tolerance to glucose starvation.
- Induces cell-cell detachment by increasing F-actin conversion to G-actin.
- Expression is induced by CD95 or TNF-alpha, via NF-kappa-B.
- Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells.
- Able to phosphorylate Ser-464 of LATS1.
- Applications:Suitable for use in Western Blot and ELISA.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Specificity：Recognizes endogenous levels of human NUAK2.
- Isotype：IgG
- Calc Applications Abbrev：E WB
- Calc Crossreactivity：Hu
- Immunogen：Synthetic peptide corresponding to human NUAK2 protein.
- Swiss Prot Number：Q9H093
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