The protein encoded by NTF3 is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons.
This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor.
It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta.
NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs.
The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.
NTF3 (Neurotrophin 3) is a Protein Coding gene.
Diseases associated with NTF3 include Hypochondriasis and Diabetic Polyneuropathy.
Among its related pathways are p70S6K Signaling and Akt Signaling.
Applications:Suitable for use in Immunohistochemistry, ELISA.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 1:50-1:200ELISA: 1:10000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human NT-3. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa180-230 from human NT-3.
