NR4A2 encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily.
The encoded protein may act as a transcription factor.
Mutations in NR4A2 have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression.
Misregulation of NR4A2 may be associated with rheumatoid arthritis.
Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of human NR4A2. Species Crossreactivity: mouse and rat
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to aa100-180 from human NR4A2.