84-5533-39　［取扱停止］NOS1, phosphorylated (Ser852) 100ul　539809

特徴

• The protein encoded by NOS1 belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine.
• Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities.
• In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection.
• This protein is ubiquitously expressed, with high level of expression in skeletal muscle.
• Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known.
• Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.
• Applications:Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry (paraffin): 1:100-1:300Immunofluorescence: 1:200-1:1000ELISA: 1:20,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.