NR4A3 (nuclear receptor subfamily 4 group A member 3) encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily.
The encoded protein may act as a transcriptional activator.
The protein can efficiently bind the NGFI-B response element (NBRE).
Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes.
The translocation breakpoints are associated with nuclear receptor subfamily 4, group A, member 3 (on chromosome 9) and either Ewing Sarcome breakpoint region 1 (on chromosome 22), RNA polymerase II, TATA box-binding protein-associated factor, 68kD (on chromosome 17), or transcription factor 12 (on chromosome 15).
Multiple transcript variants encoding different isoforms have been found for NR4A3.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:40,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human NOR-1. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa360-440 from the Internal region of human NOR-1.
