Nop56p (NOP56 ribonucleoprotein) is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin.
Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing.
The protein encoded by NOP56 is similar in sequence to Nop56p and is also found in the nucleolus.
Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36.
Multiple transcript variants encoding several different isoforms have been found for NOP56, but the full-length nature of most of them has not been determined.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:10,000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:30ul
Host:rabbit
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of NOP56. Species Crossreactivity: human, mouse and rat
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to aa191-240 from NOP56.