84-5532-91　［取扱停止］NNTM 30ul　539786

特徴

• NNT (nicotinamide nucleotide transhydrogenase) is a protein coding gene.
• Diseases associated with NNT include glucocorticoid deficiency 4, with or without mineralocorticoid deficiency and familial glucocorticoid deficiency.
• Among its related pathways are metabolism and NAD metabolism.
• NNT encodes an integral protein of the inner mitochondrial membrane.
• The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane.
• Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH.
• The resulting NADPH is used for biosynthesis and in free radical detoxification.
• Applications:Suitable for use in Western Blot and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.