The natural cytotoxicity triggering receptor 3 encoded by NCR3 is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells.
The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor.
A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility.
Three transcript variants encoding different isoforms have been found for this gene.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:40,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of human NKp30. Species Crossreactivity: rat
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu Rt
Immunogen:Synthetic peptide corresponding to aa80-160 of human NKp30.