NKAP encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB.
This protein is associated with the the histone deacetylase HDAC3 and with the notch corepressor complex, and it thereby acts as a transcriptional repressor of notch target genes.
It is also required for alphabeta T cell development.
A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Rec:ommended Dilution:Western Blot 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human NKAP.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa10-90 from human NKAP.
