NBEAL1 (neurobeachin-like 1), also known as ALS2CR16 (amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) or ALS2CR17, is a 2694aa protein that belongs to the WD repeat Neurobeachin family.
While highly expressed in kidney, brain, prostate and testis, NBEAL1 is also found at low levels in peripheral blood leukocytes, small intestine, ovary and colon.
NBEAL1 contains one BEACH domain and two WD repeats, and undergoes alternative splicing to produce two isoforms.
NBEAL2 (neurobeachin-like protein 2), also known as GPS or BDPLT4, is a 2754aa protein that belongs to the WD repeat neurobeachin family.
Existing as four alternatively spliced isoforms, NBEAL2 contains one BEACH domain and five WD repeats.
NBEAL2 is thought to play a role in α-granule biogenesis in megakaryocytes and is encoded by a gene that maps to human chromosome 3p21.1.
Applications:Suitable for use in Western Blot, Immunohistochemistry, and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry (paraffin): 1:100-1:300ELISA: 1:10,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human NBEAL1.
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa540-620 from the Internal region of human NBEAL1.
