84-5524-69　［取扱停止］Myosin IXb 30ul　539369

特徴

• MYO9B encodes a member of the myosin family of actin-based molecular motor heavy chain proteins.
• The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9).
• The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain.
• The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end.
• The protein also has rho-GTPase activity.
• Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility.
• Multiple transcript variants encoding different isoforms have been found for MYO9B.
• Applications:Suitable for use in Western Blot and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:10,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.