MYO9B encodes a member of the myosin family of actin-based molecular motor heavy chain proteins.
The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9).
The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain.
The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end.
The protein also has rho-GTPase activity.
Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility.
Multiple transcript variants encoding different isoforms have been found for this gene.
Applications:Suitable for use in Western Blot, Immunohistochemistry, and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry (paraffin): 1:100-1:300ELISA: 1:5000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human MyoD (phospho Ser200). Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human MyoD around the phosphorylation site of S200.
