Diseases associated with MYO1A include Dfna48 nonsyndromic hearing loss and deafness and deafness, autosomal dominant 48.
Among its related pathways are Sertoli-Sertoli cell junction dynamics and actin nucleation by ARP-WASP complex.
MYO1A encodes a member of the myosin superfamily.
The protein represents an unconventional myosin; it should not be confused with the conventional skeletal muscle myosin-1 (MYH1).
Unconventional myosins contain the basic domains characteristic of conventional myosins and are further distinguished from class members by their tail domains.
They function as actin-based molecular motors.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human MYO1A. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa370-450 from human MYO1A.
