Myogenic Factor 5 acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis.
Induces fibroblasts to differentiate into myoblasts.
Probable sequence specific DNA-binding protein.
Diseases associated with MYF5 include skeletal muscle cancer and botryoid rhabdomyosarcoma.
Among its related pathways are Developmental Biology and CDO in myogenesis.
Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding and RNA polymerase II core promoter proximal region sequence-specific DNA binding.
An important paralog of this gene is MYOD1.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:40,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human Myf-5. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to aa30-110 of human Myf-5.
