Diseases associated with MYO18B include Klippel-Feil syndrome 4, autosomal recessive, With myopathy and facial dysmorphism and Klippel-Feil syndrome 4.
Among its related pathways are Sertoli-Sertoli cell junction dynamics and actin nucleation by ARP-WASP complex.
The protein encoded by MYO18B may regulate muscle-specific genes when in the nucleus and may influence intracellular trafficking when in the cytoplasm.
The encoded protein functions as a homodimer and may interact with F actin.
Mutations in MYO18B are associated with lung cancer.
Applications:Suitable for use in Immunohistochemistry (paraffin).
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 1:50-1:300Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human MY18B.
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa1680-1760 from human MY18B.
