84-5522-80 ［取扱停止］mTOR, phosphorylated (Thr2446) 30ul 539256
特徴
- Mechanistic target of rapamycin encoded by MTOR belongs to a family of phosphatidylinositol kinase-related kinases.
- These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation.
- Mechanistic target of rapamycin acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.
- The ANGPTL7 gene is located in an intron of MTOR.
- Applications:Suitable for use in Western Blot and ELISA.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:10,000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：30ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
- Specificity：Recognizes endogenous levels of human mTOR (phospho Thr2446). Species Crossreactivity: mouse, rat
- Isotype：IgG
- Calc Applications Abbrev：E WB
- Calc Crossreactivity：Hu Mo Rt
- Immunogen：Synthetic peptide corresponding to human mTOR around the phosphorylation site of T2446.
- Swiss Prot Number：P42345
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