The product of STK26 (serine/threonine kinase 26) is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases.
The encoded protein contains an N-terminal kinase domain, and a C-terminal regulatory domain that mediates homodimerization.
The protein kinase localizes to the golgi apparatus and is specifically activated by binding to the golgi matrix protein GM130.
It is also cleaved by caspase-3 in vitro, and may function in the apoptotic pathway.
Several alternatively spliced transcript variants of STK26 have been described, but the full-length nature of some of these variants has not been determined.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:30ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of human MST4. Species Crossreactivity: mouse
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu Mo
Immunogen:Synthetic peptide corresponding to aa320-400 from human MST4.