84-5522-03　［取扱停止］MRP6 30ul　539214

特徴

• ABCC6 (ATP binding cassette subfamily C member 6) is a protein coding gene.
• Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and photodynamic therapy-induced NFE2L2 (NRF2) survival signaling.
• The protein encoded by ABCC6 is a member of the superfamily of ATP-binding cassette (ABC) transporters.
• ABC proteins transport various molecules across extra- and intra-cellular membranes.
• ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
• The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance.
• Mutations in ABCC6 cause pseudoxanthoma elasticum.
• Alternatively spliced transcript variants that encode different proteins have been described for ABCC6.
• Applications:Suitable for use in Western Blot and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.